Making every disease treatable by making the total human genome druggable.

Applying revolution­ary chemical biology technologies to create life-changing covalent therapeutics for untreatable diseases.

Researchers have discovered hundreds of drug targets to treat disease—and find more every day. But 90% of these targets are now considered undruggable,” and therefore untreatable. 

With the power of covalent bonding and our proprietary technology platform for high-throughput drug discovery, Totus Medicines converts genetic discoveries into real drugs.

We have the power to treat cancer, alzheimers, infectious diseases, even aging. Within this decade.

01 Power

Covalency—an unbreakable bond between a drug and its target—is the universal key for safe, effective drugs like penicillin, aspirin, and AZT.

02 Scale

The Totus Platform solves the challenges of covalent drug discovery with speed and precision.

03 Impact

We’re focused on the most profound human needs; starting with resistant cancer mutations.

Totus Medicines.
Our life’s work is
to save lives.

Join a Revolution in
Chemical Biology

Our Team

Totus Medicines is looking for brilliant scientists. Scientists who want to create real drugs that make a real difference in millions of people’s lives today, and for years to come.

Nir London

Weizmann Institute of Science

Nabeel Bardeesy

Massachusetts General Hospital

Cyril Benes

Massachusetts General Hospital

Avner Schlessinger

Icahn School of Medicine
at Mount Sinai

Sarat Chandarlapaty

Memorial Sloan Kettering
Cancer Center